Knowledge Management System Of Institute of Earth Environment, CAS
| Ancient DNA and deep population structure in sub-Saharan African foragers | |
| Lipson, Mark1,2; Sawchuk, Elizabeth A.3,4; Thompson, Jessica C.5,6; Oppenheimer, Jonas7; Tryon, Christian A.8,9,10; Ranhorn, Kathryn L.6; de Luna, Kathryn M.11; Sirak, Kendra A.1,2; Olalde, Inigo1,12; Ambrose, Stanley H.13; Arthur, John W.14; Arthur, Kathryn J. W.14; Ayodo, George15; Bertacchi, Alex5; Cerezo-Roman, Jessica I.16; Culleton, Brendan J.17; Curtis, Matthew C.18; Davis, Jacob; Gidna, Agness O.19; Hanson, Annalys20; Kaliba, Potiphar21; Katongo, Maggie22,23; Kwekason, Amandus19; Laird, Myra F.24; Lewis, Jason4; Mabulla, Audax Z. P.25; Mapemba, Fredrick21; Morris, Alan26; Mudenda, George23; Mwafulirwa, Raphael27; Mwangomba, Daudi28; Ndiema, Emmanuel29; Ogola, Christine29; Schilt, Flora30; Willoughby, Pamela R.3; Wright, David K.31,32; Zipkin, Andrew33; Pinhasi, Ron34,35; Kennett, Douglas J.36; Manthi, Fredrick Kyalo29; Rohland, Nadin1; Patterson, Nick2; Reich, David1,2,37,38; Prendergast, Mary E.1,22 | |
| 通讯作者 | Lipson, Mark(mlipson@genetics.med.harvard.edu) ; Sawchuk, Elizabeth A.(esawchuk@ualberta.ca) ; Thompson, Jessica C.(jessica.thompson@yale.edu) ; Reich, David(reich@genetics.med.harvard.edu) ; Prendergast, Mary E.(mary@rice.edu) |
| 2022-02-23 | |
| 发表期刊 | NATURE
 |
| ISSN | 0028-0836 |
| 页码 | 24 |
| 摘要 | Multiple lines of genetic and archaeological evidence suggest that there were major demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of sub-Saharan Africa(1-4). Inferences about this period are challenging to make because demographic shifts in the past 5,000 years have obscured the structures of more ancient populations(3,5). Here we present genome-wide ancient DNA data for six individuals from eastern and south-central Africa spanning the past approximately 18,000 years (doubling the time depth of sub-Saharan African ancient DNA), increase the data quality for 15 previously published ancient individuals and analyse these alongside data from 13 other published ancient individuals. The ancestry of the individuals in our study area can be modelled as a geographically structured mixture of three highly divergent source populations, probably reflecting Pleistocene interactions around 80-20 thousand years ago, including deeply diverged eastern and southern African lineages, plus a previously unappreciated ubiquitous distribution of ancestry that occurs in highest proportion today in central African rainforest hunter-gatherers. Once established, this structure remained highly stable, with limited long-range gene flow. These results provide a new line of genetic evidence in support of hypotheses that have emerged from archaeological analyses but remain contested, suggesting increasing regionalization at the end of the Pleistocene epoch. DNA analysis of 6 individuals from eastern and south-central Africa spanning the past approximately 18,000 years, and of 28 previously published ancient individuals, provides genetic evidence supporting hypotheses of increasing regionalization at the end of the Pleistocene. |
| DOI | 10.1038/s41586-022-04430-9 |
| 关键词[WOS] | HUNTER-GATHERERS ; GENOME SEQUENCE ; STONE-AGE ; HISTORY ; MIGRATION ; ADMIXTURE ; ORIGIN ; MTDNA ; CAVE ; TREE |
| 收录类别 | SCI ; SCI |
| 语种 | 英语 |
| 资助项目 | NSF Archaeometry programme[BCS-1460369] ; National Geographic Society[NGS-53412R-18] ; Yale University ; Hyde Family Foundations ; Social Sciences and Humanities Research Council of Canada[756-2017-0456] ; Social Sciences and Humanities Research Council of Canada[BPF 169449] ; Radcliffe Institute for Advanced Study ; NIH[R01-GM100233] ; NIH[R01-HG012287] ; John Templeton Foundation[61220] ; Allen Discovery Center programme, a Paul G. Allen Frontiers Group advised programme of the Paul G. Allen Family Foundation |
| WOS研究方向 | Science & Technology - Other Topics |
| 项目资助者 | NSF Archaeometry programme ; National Geographic Society ; Yale University ; Hyde Family Foundations ; Social Sciences and Humanities Research Council of Canada ; Radcliffe Institute for Advanced Study ; NIH ; John Templeton Foundation ; Allen Discovery Center programme, a Paul G. Allen Frontiers Group advised programme of the Paul G. Allen Family Foundation |
| WOS类目 | Multidisciplinary Sciences |
| WOS记录号 | WOS:000760257200004 |
| 出版者 | NATURE PORTFOLIO |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.ieecas.cn/handle/361006/17512 |
| 专题 | 黄土与第四纪地质国家重点实验室（2010~） |
| 通讯作者 | Lipson, Mark; Sawchuk, Elizabeth A.; Thompson, Jessica C.; Reich, David; Prendergast, Mary E. |
| 作者单位 | 1.Harvard Med Sch, Dept Genet, Boston, MA 02115 USA 2.Harvard Univ, Dept Human Evolutionary Biol, Cambridge, MA 02114 USA 3.Univ Alberta, Dept Anthropol, Edmonton, AB, Canada 4.SUNY Stony Brook, Dept Anthropol, Stony Brook, NY 11794 USA 5.Yale Univ, Dept Anthropol, Peabody Museum Nat Hist, New Haven, CT 06520 USA 6.Arizona State Univ, Inst Human Origins, Sch Human Evolut & Social Change, Tempe, AZ 85281 USA 7.Univ Calif Santa Cruz, Dept Biomol Engn, Santa Cruz, CA USA 8.Univ Connecticut, Dept Anthropol, Storrs, CT USA 9.Harvard Univ, Dept Anthropol, Cambridge, MA USA 10.Smithsonian Inst, Human Origins Program, Natl Museum Nat Hist, Washington, DC USA 11.Georgetown Univ, Dept Hist, Washington, DC USA 12.Univ Basque Country UPV EHU, BIOMICs Res Grp, Vitoria, Spain 13.Univ Illinois, Dept Anthropol, Urbana, IL USA 14.Univ S Florida, Dept Anthropol, Petersburg, FL USA 15.Jaramogi Oginga Odinga Univ Sci & Technol, Sch Hlth Sci, Bondo, Kenya 16.Univ Oklahoma, Dept Anthropol, Norman, OK USA 17.Penn State Univ, Inst Energy & Environm, University Pk, PA USA 18.Calif State Univ Channel Isl, Anthropol Program, Camarillo, CA USA 19.Natl Museums Tanzania, Dar Es Salaam, Tanzania 20.Sol Solut LLC, Scottsdale, AZ USA 21.Malawi Dept Museums & Monuments, Lilongwe, Malawi 22.Rice Univ, Dept Anthropol, Houston, TX USA 23.Livingstone Museum, Livingstone, Zambia 24.Univ Southern Calif, Dept Integrat Anatom Sci, Los Angeles, CA USA 25.Univ Dar Es Salaam, Dept Archeol & Heritage Studies, Dar Es Salaam, Tanzania 26.Univ Cape Town, Dept Human Biol, Cape Town, South Africa 27.Mzuzu Univ, Mzuzu, Malawi 28.Univ Malawi, Zomba, Malawi 29.Natl Museums Kenya, Dept Earth Sci, Nairobi, Kenya 30.Univ Algarve, Interdisciplinary Ctr Archeol & Evolut Human Beha, FCHS, Faro, Portugal 31.Univ Oslo, Dept Archeol Conservat & Hist, Oslo, Norway 32.Chinese Acad Sci, Inst Earth Environm, State Key Lab Loess & Quaternary Geol, Xian, Peoples R China 33.Arizona State Univ, Sch Human Evolut & Social Change, Tempe, AZ USA 34.Univ Vienna, Dept Evolutionary Anthropol, Vienna, Austria 35.Univ Vienna, Human Evolut & Archaeol Sci HEAS, Vienna, Austria 36.Univ Calif Santa Barbara, Dept Anthropol, Santa Barbara, CA USA 37.Broad Inst Harvard & MIT, Cambridge, MA 02142 USA 38.Harvard Med Sch, Howard Hughes Med Inst, Boston, MA 02115 USA |
| 推荐引用方式 GB/T 7714 | Lipson, Mark,Sawchuk, Elizabeth A.,Thompson, Jessica C.,et al. Ancient DNA and deep population structure in sub-Saharan African foragers[J]. NATURE,2022:24. |
| APA | Lipson, Mark.,Sawchuk, Elizabeth A..,Thompson, Jessica C..,Oppenheimer, Jonas.,Tryon, Christian A..,...&Prendergast, Mary E..(2022).Ancient DNA and deep population structure in sub-Saharan African foragers.NATURE,24. |
| MLA | Lipson, Mark,et al."Ancient DNA and deep population structure in sub-Saharan African foragers".NATURE (2022):24. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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