Ecotoxicity assessment of a molybdenum mining effluent using acute lethal, oxidative stress, and osmoregulatory endpoints in zebrafish (Danio rerio)

doi:10.1007/s11356-020-10841-w

IEECAS OpenIR > 生态环境研究室

	Ecotoxicity assessment of a molybdenum mining effluent using acute lethal, oxidative stress, and osmoregulatory endpoints in zebrafish (Danio rerio)
	Chen, Dong 1,2; Zhang, Jing 1,2; Chen, Yi-ping 1
通讯作者	Chen, Yi-ping(chenyp@ieecas.cn)
	2020-09-21
发表期刊	ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
ISSN	0944-1344
页码	12
摘要	The present study investigated the ecotoxicity of raw mining effluent from the largest molybdenum (Mo) open-pit mine in the Qinling mountains, China, and the treated effluent with neutralization and coagulation/adsorption processes, using zebrafish (Danio rerio). The results showed the following: (1) the mining effluent is acid mine drainage (AMD) and is highly toxic to zebrafish with a 96-h median lethal concentration (LC50) of 3.80% (volume percentage) of the raw effluent; (2) sublethal concentrations of the raw effluent (1/50, 1/10, and 1/2 96-h LC50) induced oxidative stress and osmoregulatory impairment, as reflected by the alterations in activities of superoxide dismutase and catalase and contents of malondialdehyde, and inhibition of Na+, K+-ATPase activity in gills and muscle after 28 days of sub-chronic exposure when compared with the unexposed group; and (3) the treatment of the raw effluent with neutralizer (NaOH) and adsorbent activated carbon reduced the acute lethal effect of raw effluent. The used endpoints including acute lethal and biochemical parameters related to oxidative stress and osmoregulatory impairment in zebrafish are cost-effective for toxicity assessment of AMD like the studied Mo mining effluent. Mining effluent management strategies extended by these results, i.e., the restriction of discharging raw and diluted effluent to adjacent waterways and the introduction of bio-monitoring system across all mining drainages in this area, were also proposed and discussed.
关键词	Acid mine drainage Median lethal concentration Enzymatic antioxidant Na+ K+-ATPase Wastewater treatment Environmental management
DOI	10.1007/s11356-020-10841-w
关键词[WOS]	ACID-MINE DRAINAGE ; OREOCHROMIS-NILOTICUS ; BENTONITE CLAY ; ACUTE TOXICITY ; HEAVY-METALS ; WASTE-WATER ; BIOMARKERS ; POLLUTION ; FISH ; ANTIOXIDANT
收录类别	SCI ; SCI
语种	英语
资助项目	Science and Technology Service Network Initiative (STS) of the Chinese Academy of Sciences[KFJ-EWSTS-124] ; University of Chinese Academy of Sciences (UCAS)[2017-71]
WOS研究方向	Environmental Sciences & Ecology
项目资助者	Science and Technology Service Network Initiative (STS) of the Chinese Academy of Sciences ; University of Chinese Academy of Sciences (UCAS)
WOS类目	Environmental Sciences
WOS记录号	WOS:000571705600004
出版者	SPRINGER HEIDELBERG
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ieecas.cn/handle/361006/15315
专题	生态环境研究室
通讯作者	Chen, Yi-ping
作者单位	1.Chinese Acad Sci, Inst Earth Environm, State Key Lab Loess & Quaternary Geol, 97 Yanxiang Rd, Xian 710061, Shaanxi, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Chen, Dong,Zhang, Jing,Chen, Yi-ping. Ecotoxicity assessment of a molybdenum mining effluent using acute lethal, oxidative stress, and osmoregulatory endpoints in zebrafish (Danio rerio)[J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,2020:12.
APA	Chen, Dong,Zhang, Jing,&Chen, Yi-ping.(2020).Ecotoxicity assessment of a molybdenum mining effluent using acute lethal, oxidative stress, and osmoregulatory endpoints in zebrafish (Danio rerio).ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,12.
MLA	Chen, Dong,et al."Ecotoxicity assessment of a molybdenum mining effluent using acute lethal, oxidative stress, and osmoregulatory endpoints in zebrafish (Danio rerio)".ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020):12.